Thyroid Peroxidase (TPO) Mouse Monoclonal Antibody (PT0857) - RA12078

Thyroid Peroxidase (TPO) Mouse Monoclonal Antibody (PT0857)

Size: 50μL, 100μL

Catalogue Numbers: RA12078-50, RA12078-100

Citations, Manuals and MSDS Available upon request.

Background: thyroid peroxidase (TPO) Homo sapiens This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 7173

SWISS: P07202

Source: Mouse

Research Use Only