Product Description

Thyroid Peroxidase (TPO) Mouse Monoclonal Antibody (PT0857)

Sizes: 50μL, 100μL

Catalogue Numbers: RA12078-50, RA12078-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: thyroid peroxidase (TPO) Homo sapiens This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: Thyroid peroxidase (TPO) (EC 1.11.1.8)

Clonality: Monoclonal

Dilution: WB 1:500-2000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 7173

Research Use Only