Thyroid Transcription Factor 1 Monoclonal Antibody-MB11733

Thyroid Transcription Factor 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11733-50, MB11733-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P43699

Host: Rabbit

Reactivity: Human, Hamster

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Thyroid Transcription Factor 1 in K562 using Thyroid Transcription Factor 1 antibody, and DAPI., Western blot analysis of TTF1 in K562, CHO-K1, Hela lysates using TTF1 antibody.

Alternative Name: NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1

Immunogen: A synthetic peptide of human TTF1

Conjugate: Unconjugated

Modification: Unmodified