Tie-1 rabbit pAb - ES7394

Tie-1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7394-50, ES7394-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Alternate Name: TIE1; TIE; Tyrosine-protein kinase receptor Tie-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 130kD

Human Gene ID: 7075

Human SWISS Prot NO: P35590

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only