TIM50 Rabbit Polyclonal Antibody - BT-AP05119

TIM50 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05119-20, BT-AP05119-50, BT-AP05119-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal| or presequence| on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier| and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis.

Research Areas: Signal transduction; Metabolism

Target Protein: TIMM50

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TIM50

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q3ZCQ8; Mouse: Q9D880

Synonyms: TIM50; Mitochondrial import inner membrane translocase subunit TIM50

GeneID: Human: 92609; Mouse: 66525

Research Use Only