Product Description

TIMP-1 (G94) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1697-50, BS1697-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resμlting in irreversible inactivation of the metalloproteinase.TIMP-1 was found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regμlator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regμlating trophoblastic invasion of the uterus as well as in regμlating remodeling of the extracellμlar matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 61-110 of Human TIMP-1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TIMP-1 (G94) polyclonal antibody detects endogenous levels of TIMP-1 protein.

Molecular Weight: ~ 23 kDa

Pathway: Tumor Angiogenesis, Contribution of ECM and Cytoskeletal Factors to EMT,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01033

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only