TIN2 rabbit pAb - ES5486

TIN2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5486-50, ES5486-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],

Alternate Name: TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 53kD

Human Gene ID: 26277

Human SWISS Prot NO: Q9BSI4

Subcellular Location: Nucleus. Chromosome, telomere. Associated with telomeres.; [Isoform 1]: Nucleus matrix.

Research Use Only