TLE2 rabbit pAb - ES7399

TLE2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7399-50, ES7399-100

Citations, Manuals and MSDS Available upon request.

Background: function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 6 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5., tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.,

Alternate Name: TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 110kD

Human Gene ID: 7089

Human SWISS Prot NO: Q04725

Subcellular Location: Nucleus

Research Use Only