TLE3 rabbit pAb - ES12682

TLE3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12682-50, ES12682-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

Alternate Name: Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human TLE3 AA range: 257-307

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 7090

Human SWISS Prot NO: Q04726

Subcellular Location: Nucleus

Research Use Only