Product Description

TLE4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30519-50, RA30519-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation., function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 7 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2., tissue specificity:In all tissues examined, mostly in brain, and muscle.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: TLE4, KIAA1261, Transducin-like enhancer protein 4

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 83

Protein Molecular Weight (kDa): 83

Storage: -20°C/1 year

Human Gene ID: 7091

Human SwissProt Number: Q04727

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only