Product Description

TLR2 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS49188-50, BS49188-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecμles derived from microorganisms known as pathogen-associated molecμlar patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regμlation of signaling pathways to modμlate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Jan 2016]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: TIL4, CD282

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human TLR2

Dilution: WB: 1:1000 ICC/IF: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 90 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60603

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only