TLR8 rabbit pAb - ES20603

TLR8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20603-50, ES20603-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008],

Alternate Name: Toll-like receptor 8; CD288

Source: Rabbit

Applications: IHC; IF

Dilution: IHC: 1:200-500

Reactivity: Human; Mouse; Rat

Immunogen: Recombinant Protein of TLR8

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Human Gene ID: 51311

Human SWISS Prot NO: Q9NR97

Subcellular Location: Endosome membrane; Single-pass type I membrane protein. Endosomal localization confers distinctive proteolytic processing.

Research Use Only