Product Description

TMC7 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60259-50, BS60259-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein that is a member of the TMC protein family. All TMC genes encode transmembrane proteins with intracellμlar amino- and carboxy- termini and at least eight membrane spanning domains. Therefore, TMC7 is a mμlti-pass membrane protein that may regμlate or function as an ion channel or transporter. The gene encoding TMC7 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Transmembrane channel-like protein 7

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human TMC7.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TMC7 polyclonal antibody detects endogenous levels of TMC7 protein.

Molecular Weight: ~ 84 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7Z402

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only