TMC8 rabbit pAb - ES4875

TMC8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4875-50, ES4875-100

Citations, Manuals and MSDS Available upon request.

Background: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008],

Alternate Name: TMC8; EVER2; EVIN2; Transmembrane channel-like protein 8; Epidermodysplasia verruciformis protein 2

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human TMC8. AA range:601-650

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 81kD

Human Gene ID: 147138

Human SWISS Prot NO: Q8IU68

Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein.

Research Use Only