Product Description

TMED10 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19178-60, E-AB-19178-120, E-AB-19178-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TMED10

Target Synonym: 1110014C03Rik ; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; MGC102351; p23; p24 family protein delta 1; p24 family protein delta-1; p24(DELTA); p24delta; p24delta1; S31I125; S31III125; TMED 10; Tmed10; TMEDA; Tmp 21 I; Tmp 21; Tmp 21 I; Tmp-21-I; Transmembrane emp24 domain containing protein 10; Transmembrane emp24 domain-containing protein 10; Transmembrane emp24-like trafficking protein 10 (yeast); Transmembrane protein Tmp21; Transmembrane trafficking protein 21kD

Research Areas: Cancer, Neuroscience, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P49755

Background: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Concentration: 1.14 mg/mL

Immunogen: Fusion protein of human TMED10

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Calculated MW: 25 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only