TMEM145 rabbit pAb - ES3618

TMEM145 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3618-50, ES3618-100

Citations, Manuals and MSDS Available upon request.

Background: TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1, 400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Alternate Name: TMEM145; Transmembrane protein 145

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human TMEM145. AA range:58-107

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 56kD

Human Gene ID: 284339

Human SWISS Prot NO: Q8NBT3

Subcellular Location: Membrane; Multi-pass membrane protein.

Research Use Only