TMEM185A rabbit pAb - ES7761

TMEM185A rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7761-50, ES7761-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013],

Alternate Name: TMEM185A; CXorf13; FAM11A; Transmembrane protein 185A; Protein FAM11A

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human TMEM185A. AA range:290-339

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 41kD

Human Gene ID: 84548

Human SWISS Prot NO: Q8NFB2

Subcellular Location: Cell projection, dendrite. Membrane; Multi-pass membrane protein.

Research Use Only