Product Description

TMEM43 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71265-50, BS71265-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricμlar dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricμlar cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricμlar dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricμlar tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: TMEM43, ARVC5, ARVD5, EDMD7, LUMA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human TMEM43(NP_077310.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 45kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BTV4

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only