Product Description

TNF-IP 1 (S122) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2484-50, BS2484-100

Sizes: 50µl, 100µl

Swiss-Prot: Q13829

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TNF-IP 1 (S122) polyclonal antibody detects endogenous levels of TNF-IP 1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TNF-IP 1 (S122) pAb at 1:500 dilution
Lane 1: A549 whole cell lysate (40ug)
Lane 2: Hela whole cell lysate (40ug)
Lane 3: PC12 whole cell lysate (40ug)
Lane 4: 3T3-L1 whole cell lysate (40ug)
Lane 5: BV2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of TNF-IP 1 (S122) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 36 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor, alpha-induced protein 1, endothelial; TNFAIP1; BACURD2; EDP1

Immunogen: Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.

Conjugate: Unconjugated

Modification: Unmodified