Product Description

TNF14 Polyclonal Antibody

Catalogue Numbers: BS65118-50, BS65118-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: O43557

Host: Rabbit

Reactivity: Human, Mouse

Applications: IF/ICC,ELISA

All Applications: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Background: tumor necrosis factor superfamily member 14(TNFSF14) Homo sapiens The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LIGHT Polyclonal Antibody detects endogenous levels of LIGHT protein.

Extra Notes: Immunofluorescence analysis of HeLa cells, using TNF14 Antibody. The picture on the right is blocked with the synthesized peptide.

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: TNFSF14; HVEML; LIGHT; Tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand; CD antigen CD258

Immunogen: The antiserum was produced against synthesized peptide derived from human TNF14. AA range:51-100

Conjugate: Unconjugated

Modification: Unmodified