TNFRSF10B Monoclonal Antibody - BT-MCA4707

TNFRSF10B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4707-50, BT-MCA4707-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Research Areas: Signal transduction, Cardiovascular, Cancer

Target Protein: TNFRSF10B

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2H5B8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TNFRSF10B

Immunogen: Purified recombinant fragment of human TNFRSF10B (AA: extra 56-210) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 47.9kDa

UniProt Accession: O14763

Synonyms: DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5

GeneID: 8795

Research Use Only