TNK1 (phospho-Tyr277) Rabbit Polyclonal Antibody - RA30588

TNK1 (phospho-Tyr277) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30588-50, RA30588-100

Citations, Manuals and MSDS Available upon request.

Background: tyrosine kinase non receptor 1 (TNK1) Homo sapiens The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 8711

Protein MW (KDa): 75

SWISS: Q13470

Source: Rabbit

Research Use Only