TNNC1 rabbit pAb - ES12618

TNNC1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12618-50, ES12618-100

Citations, Manuals and MSDS Available upon request.

Background: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human TNNC1 AA range: 57-107

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 7134

Human SWISS Prot NO: P63316

Subcellular Location: nucleoplasm, mitochondrion, cytosol, troponin complex, actin cytoskeleton, contractile fiber,

Research Use Only