Product Description

TNNT2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91364-50, BS91364-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P45379(Human) P50752(Mouse) P50753(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:1,000-1:2,000
IHC:1:100-1:500

Background: Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interacts with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between Actin and Myosin by binding to calcium. Troponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator) and Troponin T (the link to the muscle thin filament). Troponin C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has two isoforms: fast and slow. Fast Troponin C has two calcium binding sites, while slow/cardiac Troponin C has a single calcium binding site.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-Cardiac Troponin T antibody. Counter stained with hematoxylin.

Bioworld Molecular Weight: 36 kDa

Specificity: TNNT2 polyclonal antibody detects endogenous levels of TNNT2 protein.

Alternative Name: TnTc, cTnT, TNNT2, Cardiac muscle troponin T, Cardiomyopathy dilated 1D (autosomal dominant), Cardiomyopathy hypertrophic 2, CMD1D, CMH2, CMPD2, cTnT, LVNC6, MGC3889, OTTHUMP00000033864, OTTHUMP00000033865, OTTHUMP00000033866, OTTHUMP00000033867, OTTHUMP00000033870, OTTHUMP00000218095, RCM3, TNNT 2, TNNT2, TNNT2, TnTc, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T, cardiac muscle, Troponin T2 cardiac,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified