TONSL Polyclonal Antibody - E-AB-10088

TONSL Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10088-60, E-AB-10088-120, E-AB-10088-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TONSL

Target Synonym: I kappa B related protein; I-kappa-B-related protein; IkappaBR; IKBR; Inhibitor of kappa B related protein; Inhibitor of kappa B-related protein; MMS22L-interacting protein; MMS22L-interacting protein; NFBIL2/TONSL; NF kappa B inhibitor like protein 2; NF-kappa-B inhibitor-like protein 2; NFBIL2; NFBIL2/TONSL; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; Protein IkappaBR; Tonsl; TONSL; Tonsoku-like protein; tonsoku-like; DNA repair protein

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96HA7

Background: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human TONSL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:300

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only