Product Description

TOP2A (Phospho Ser1213) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30594-50, RA30594-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA., enzyme regulation:Specifically inhibited by the intercalating agent amsacrine., function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks., miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils., PTM:Phosphorylation has no effect on catalytic activity., similarity:Belongs to the type II topoisomerase family., subcellular location:Generally located in the nucleoplasm., subunit:Homodimer. Interacts with COPS5.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: DNA topoisomerase 2-alpha (EC 5.99.1.3;DNA topoisomerase II, alpha isozyme)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 174

Protein Molecular Weight (kDa): 174

Storage: -20°C/1 year

Human Gene ID: 7153

Human SwissProt Number: P11388

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only