Topo IIIα Polyclonal Antibody - RA30596

Topo IIIα Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30596-50, RA30596-100

Citations, Manuals and MSDS Available upon request.

Background: topoisomerase (DNA) III alpha (TOP3A) Homo sapiens This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 7156

Protein MW (KDa): 115

SWISS: Q13472

Source: Rabbit

Research Use Only