Topo IIIα rabbit pAb - ES8351

Topo IIIα rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8351-50, ES8351-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Alternate Name: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from Topo IIIα . at AA range: 350-430

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 115kD

Human Gene ID: 7156

Human SWISS Prot NO: Q13472

Subcellular Location: Mitochondrion matrix.

Research Use Only