TORC1/CRTC1 (phospho-Ser151) rabbit pAb - ES12606

TORC1/CRTC1 (phospho-Ser151) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12606-50, ES12606-100

Citations, Manuals and MSDS Available upon request.

Alternate Name: CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)

Source: Rabbit

Applications: WB

Dilution: WB 1:1000-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 23373

Human SWISS Prot NO: Q6UUV9

Subcellular Location: Cytoplasm. Nucleus. Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity).

Research Use Only