Product Description

TORC2 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA12092-50, RA12092-100

Citations, Manuals and MSDS Available upon request.

Background: CREB regulated transcription coactivator 2 (CRTC2) Homo sapiens This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; FCM; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 200186

SWISS: Q53ET0

Source: Mouse

Research Use Only