Product Description

TORC2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36706-50, RA36706-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CREB regulated transcription coactivator 2 (CRTC2) Homo sapiens This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)

Clonality: Polyclonal

Dilution: WB 1:500-2000

Storage: -20°C/1 year

Human Gene ID: 200186

Human SwissProt Number: Q53ET0

Condition: Liquid in PBS containing 50% glycerol, and 0.12% sodium azide.

Research Use Only