TP53INP1 rabbit pAb - ES3629

TP53INP1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3629-50, ES3629-100

Citations, Manuals and MSDS Available upon request.

Background: function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis., induction:By adriamycin, gamma irradiation and H (2)O (2), in a p53-dependent way. At lower levels by ultraviolet irradiation., subcellular location:Concentrated in PML/POD/ND10 nuclear bodies., subunit:Interacts with TP53 and HIPK2., tissue specificity:Ubiquitously expressed.,

Alternate Name: TP53INP1; P53DINP1; SIP; Tumor protein p53-inducible nuclear protein 1; Stress-induced protein; p53-dependent damage-inducible nuclear protein 1; p53DINP1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human TP53INP1. AA range:171-220

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 27kD

Human Gene ID: 94241

Human SWISS Prot NO: Q96A56

Subcellular Location: Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

Research Use Only