Product Description

TPD52L1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8203-50, BS8203-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regμlated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regμlator of the G2/M transition, in breast cancer cells. Expression of D53 is highly upregμlated at the G2/M phase transition in breast cancer cell lines, and deregμlated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regμlator of vesicle trafficking and cell proliferation.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IF

Alternate Names: Tumor protein D53, hD53, Tumor protein D52-like 1, TPD52L1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human TPD52L1.

Dilution: IF 1:20 - 1:50

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TPD52L1 polyclonal antibody detects endogenous levels of TPD52L1 protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16890

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only