TPO Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35464-50, RA35464-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: thrombopoietin (THPO) Homo sapiens Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: THPO, MGDF, Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 38 Protein Molecular Weight (kDa): 38 Storage: -20°C/1 year Human Gene ID: 7066 Human SwissProt Number: P40225 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only