TPP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5627-20, A5627-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 61kDa
Observed Molecular Weight: 50kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1200
SWISS: O14773
Alternate Names: CLN2; GIG1; LPIC; SCAR7; TPP-1; TPP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Ubiquitin, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: TPP1
Research Use Only