Product Description

TPSAB1 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66079-50, MB66079-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tryptase is the most abundant neutral serine protease expressed in the secretory granμles of all human mast cells. Tryptase is secreted upon the coupled activation-degranμlation response of mast cells in peripheral tissues to physical factors such as trauma, toxins, venoms, endogenous mediators, and immune mechanisms (IgE-dependent and IgE-independent). Tryptase has distinct enzymatic functions that depend on the monomeric or homotetrameric state of this protein, the pH of the environment, and the presence or absence of heparin. Tryptase has the ability to cleave extracellμlar substrates such as vasoactive intestinal peptides, calcitonin gene-related peptides, fibronectins, fibrinogens, and kininogens. Tryptase is also a potent growth factor for epithelial cells, airway smooth muscle cells, and fibroblasts.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IHC

Alternate Names: TPS1, TPS2, TPSB1, Tryptase alpha/beta-1, Tryptase-1, Tryptase I, Tryptase alpha-1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human TPSAB1. The exact sequence is proprietary.

Dilution: IHC (1/100 - 1/300)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of TPSAB1 protein.

Molecular Weight: ~ 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15661

Product: Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Research Use Only