TRAF1 Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP09167-20, BT-AP09167-50, BT-AP09167-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by TRAF1 (TNF receptor associated factor 1) is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for TRAF1.
Research Areas: Cell Biology
Target Protein: TRAF1
Applications: WB, ELISA
Reactivity: Human, Mouse
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: TRAF1 Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 46164
UniProt Accession: Human: Q13077; Mouse: P39428
Synonyms: TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
GeneID: Human: 7185; Mouse: 22029
Research Use Only