TRAF1 Polyclonal Antibody - RA35479

TRAF1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35479-50, RA35479-100

Citations, Manuals and MSDS Available upon request.

Background: TNF receptor associated factor 1 (TRAF1) Homo sapiens The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV) . EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000

Alternative Names: TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 7185

Protein MW (KDa): 46

SWISS: Q13077

Source: Rabbit

Research Use Only