Product Description

TRAF1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35479-50, RA35479-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TNF receptor associated factor 1 (TRAF1) Homo sapiens The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)

Clonality: Polyclonal

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 46

Protein Molecular Weight (kDa): 46

Storage: -20°C/1 year

Human Gene ID: 7185

Human SwissProt Number: Q13077

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only