TRAFD1 Polyclonal Antibody - E-AB-10658

TRAFD1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10658-60, E-AB-10658-120, E-AB-10658-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRAFD1

Target Synonym: FLN29; FLN29 gene product; Protein FLN29; TRAD1; TRAF type zinc finger domain containing 1; TRAF type zinc finger domain containing protein 1; TRAF-type zinc finger domain-containing protein 1; TRAFD 1; TRAFD1

Research Areas: Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O14545

Background: The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human TRAFD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Calculated MW: 65kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only