Product Description

TRIB1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS70782-50, BS70782-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regμlates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (By similarity. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity. Interacts with MAPK kinases and regμlates activation of MAP kinases, but has no kinase activity.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: TRIB1, C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human TRIB1(NP_079471.1).

Dilution: WB, 1:1000 - 1:4000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 38kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96RU8

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only