TRIB3 Polyclonal Antibody - BT-AP15143

TRIB3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15143-20, BT-AP15143-50, BT-AP15143-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.

Research Areas: Signal transduction; Cell biology; Cardiovascular

Target Protein: TRIB3

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Tribbles homolog 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96RU7; Mouse: Q8K4K2; Rat: Q9WTQ6

Synonyms: Tribbles homolog 3;TRB-3;Neuronal cell death-inducible putative kinase;SINK;p65-interacting inhibitor of NF-kappa-B

GeneID: Human: 57761

Research Use Only