Product Description

TRIM21 (5B9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3109-50, MB3109-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P19474

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TRIM21 in MCF-7, 293T and HelaLysates using TRIM21 antibody.

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 50 kDa

Specificity: IgG1

Alternative Name: SSA; RO52; SSA1; RNF81; Ro/SSA

Immunogen: Purified recombinant human TRIM21 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified