Product Description

TRIM24 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4029-25, MB4029-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: IHC, WB

Alternate Names: Transcription intermediary factor 1-alpha, EC:2.3.2.27 , TIF1-alpha, E3 ubiquitin-protein ligase Trim24, RING-type E3 ubiquitin transferase TIF1-alpha , Tripartite motif-containing protein 24

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Human recombinant protein fragment corresponding to amino acids 706-1016 of human TRIM24 (NP_003843) produced in E.coli.

Dilution: WB 1:2000, IHC 1:150

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: ~ 117 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O15164

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only