TRIM24 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10546-20, A10546-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 117kDa
Observed Molecular Weight: 117kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8805
SWISS: O15164
Alternate Names: PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; TRIM24
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Nuclear hormone receptors, Signal Transduction, MAPK-Erk Signaling Pathway.
NCBI Alias: TRIM24
Research Use Only