Product Description

TriMethyl-Histone H3 (Lys27) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11844-50, MB11844-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template. Histones thereby play a central role in transcription regμlation, DNA repair, DNA replication and chromosomal stability.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, IHC-F, IHC-P, ICC/IF, IP, ChIP

Alternate Names: H3K27me3, H3 histone, HIST1H3A, Histone cluster 1, H3a

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Methylated

Immunogen: A synthetic methyl-peptide corresponding to residues surrounding Lys27 of human Histone H3

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 15 kDa, Observed MW: 15 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P68431

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only