Trk A Monoclonal Antibody - RA12110

Trk A Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA12110-50, RA12110-100

Citations, Manuals and MSDS Available upon request.

Background: neurotrophic receptor tyrosine kinase 1 (NTRK1) Homo sapiens This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 4914

SWISS: P04629

Source: Mouse

Research Use Only