Product Description

TRMT61B Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62465-60, E-AB-62465-120, E-AB-62465-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRMT61B

Target Synonym: TRMT61B

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9BVS5

Background: Methyltransferase that catalyzes the formation of N(1-methyladenine at position 58 (m1A58 in various tRNAs in mitochondrion, including tRNA(Leu (deciphering codons UUA or UUG, tRNA(Lys and tRNA(Ser (deciphering codons UCA, UCU, UCG or UCC. Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function. In addition to tRNA N(1-methyltransferase activity, also acts as a mRNA N(1-methyltransferase by mediating methylation of adenosine residues at the N(1 position of MT-ND5 mRNA, leading to interfere with mitochondrial translation.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human TRMT61B

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 52kDa

Observed MW: 52kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only