Troponin I-C Polyclonal Antibody - RA21291

Troponin I-C Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21291-50, RA21291-100

Citations, Manuals and MSDS Available upon request.

Background: troponin I3, cardiac type (TNNI3) Homo sapiens Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM) . [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7137

Protein MW (KDa): 26

SWISS: P19429

Source: Rabbit

Research Use Only