Product Description

Troponin I3 (K39) Polyclonal Antibody

Catalogue Numbers:BS1602-50, BS1602-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P19429

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 28 kDa

Specificity: TNNI3/Troponin I (K39) polyclonal antibody detects endogenous levels of TNNI3/Troponin I protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Troponin I, cardiac muscle; Cardiac troponin I; TNNI3; TNNC1

Immunogen: Synthetic peptide, corresponding to amino acids 100-60 of Human Troponin I3.

Conjugate: Unconjugated

Modification: Unmodified