Troponin T-C rabbit pAb - ES4092

Troponin T-C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4092-50, ES4092-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008],

Alternate Name: TNNT2; Troponin T, cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human TNNT2. AA range:131-180

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 7139

Human SWISS Prot NO: P45379

Subcellular Location: cytosol, troponin complex, striated muscle thin filament, sarcomere,

Research Use Only