TRPV4 rabbit pAb - ES3770

TRPV4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3770-50, ES3770-100

Citations, Manuals and MSDS Available upon request.

Background: transient receptor potential cation channel subfamily V member 4 (TRPV4) Homo sapiens This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Alternate Name: TRPV4; VRL2; VROAC; Transient receptor potential cation channel subfamily V member 4; TrpV4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human TRPV4. AA range:417-466

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 98kD

Human Gene ID: 59341

Human SWISS Prot NO: Q9HBA0

Subcellular Location: Cell membrane. Apical cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Cell projection, cilium. Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum.; [Isoform 1]: Cell membrane.; [Isoform 5]: Cell membrane.; [Isoform 2]: Endoplasmic reticulum.; [Isoform 4]: Endoplasmic reticulum.; [Isoform 6]: Endoplasmic reticulum.

Research Use Only